Search results for "Peroxiredoxin 6"

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Role of peroxiredoxin 6 in the chondroprotective effects of microvesicles from human adipose tissue-derived mesenchymal stem cells

2021

Este artículo se encuentra disponible en la página web de la revista en la siguiente URL: https://www.sciencedirect.com/science/article/pii/S2214031X21000656?via%3Dihub Background: Osteoarthritis (OA) is a joint disease characterized by cartilage degradation, low-grade synovitis and subchondral bone alterations. In the damaged joint, there is a progressive increase of oxidative stress leading to disruption of chondrocyte homeostasis. The modulation of oxidative stress could control the expression of inflammatory and catabolic mediators involved in OA. We have previously demonstrated that extracellular vesicles (EVs) present in the secretome of human mesenchymal stem cells from adipose tissu…

Peroxiredoxin 6Adipose tissue-derived mesenchymal stem cellsCélulas madre - Uso terapéutico.Joints - Inflammation - Treatment.Adipose tissueOsteoarthritis - Treatment.InflammationDiseases of the musculoskeletal systemmedicine.disease_causeChondrocyteStem cells - Therapeutic use.ChondrocytesDownregulation and upregulationOsteoarthritismedicineCartilage - Diseases - Treatment.Orthopedics and Sports MedicineCartílagos - Enfermedades - Tratamiento.Osteoartritis - Tratamiento.Estrés oxidativo.ChemistryAutophagyMesenchymal stem cellArticulaciones - Enfermedades - Tratamiento.Joints - Diseases - Treatment.Extracellular vesiclesMicrovesiclesCell biologyOxidative stress.medicine.anatomical_structureRC925-935Oxidative stressOriginal Articlemedicine.symptomArticulaciones - Inflamación - Tratamiento.Oxidative stressJournal of Orthopaedic Translation

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